Orthopaedic Biomechanics Laboratories
Methods and Materials Research
MSU's OBL has been performing
research to develop efficient surgical methods and cutting-edge medical
products. Below is a description of a couple recent studies conducted
in the OBL.
Material Development and Evaluation
recently assisted in the development of surgical procedure and material
to repair a torn rotator cuff tendon (RCT). The procedure involved
the utilization of a swine small intestine submucosa (SIS), developed
at Purdue University. Our investigators have also co-authored the
year 2000 O'Donoghue Award winning paper that was recently published
in the American Journal of Sports
Medicine entitled "Tissue-Engineered Rotator Cuff Tendon
Using Porcine Small Intestine Submucosa" (29(2):175-184) (Abstract).
This manuscript described the basic science research conducted at
MSU and the OBL that resulted in development of the Restore Orthobiologic
Inplant DePuy Inc. This product
was recently advertised in the American Journal of Sports Medicine
and highlighted some of the biomechanical test data generated at
The Restore (TM) Orthobiologic Implant;
Advertisement from the American Journal of Sports Medicine which
shows biomechanical test data ( see the lower right image) generated
in the OBL study.
OBL is currently evaluating several bone repair materials in studies
with DePuy Inc. The studies,
using the lapine tibial defect model, are shown at the right. Investigators
have quantified the torsional strength of repaired defect sites
over time and compared these strengths to those seen in normal and
unrepaired tibias. Similar studies have been conducted at the OBL
using the lapine radius, segmental defect model. |
testing of the lapine proximal tibia
Tibiotarsal bone plate with a 130 degree bend. Right: The hindlimb
construct mounted in the servo-hydraulic test machine with rotary
encoders at the ends of the construct and a network of strain
gauges on the plate.
investigators are also conducting experiments to develop more optimum
surgical methods to improve the strength of surgical repairs. In
a recent study the OBL has worked with Dr.
Loic DeJardin and the College
of Veterinary Medicine to validate a surgical procedure developed
at MSU to increase the fatigue strength of surgically repaired canine
tibiotarsal joints. In this biomechanical study on the canine hindlimb
preparation the OBL used strain gauges mounted to the bone plates
to test the efficacy of an added IM rod to this surgical procedure.
Compressive loading of the construct verified an increase in fatigue
life of the surgical procedure, via a reduction in plate strains
and an increase in the structural stability of the hindlimb preparation
with the addition of an IM rod into the tibia. These data are currently
being prepared for publication in the veterinary orthopaedics literature.
Attn: Dr. Roger Haut
East Fee Hall
965 Fee Road, Room A-407
East Lansing, MI 48824
by MSU OBL.
All Rights Reserved.